Salt bridges gate α-catenin activation at intercellular junctions
نویسندگان
چکیده
منابع مشابه
The cadherin-11 cytoplasmic juxtamembrane domain promotes alpha-catenin turnover at adherens junctions and intercellular motility.
Cadherins mediate homophilic cell adhesion and contribute to tissue morphogenesis and architecture. Cadherin cell adhesion contacts are actively remodeled and impact cell movement and migration over other cells. We found that expression of a mutant cadherin-11 lacking the cytoplasmic juxtamembrane domain (JMD) diminished the turnover of alpha-catenin at adherens junctions as measured by fluores...
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ژورنال
عنوان ژورنال: Molecular Biology of the Cell
سال: 2018
ISSN: 1059-1524,1939-4586
DOI: 10.1091/mbc.e17-03-0168